ALOX15B

Across TCGA patient cohorts, ALOX15B mutation is significantly associated with the RNA expression of many other genes, with 3,512 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALOX15B-associated genes across cancer lineages are TCF19, MED9, and MIR3115. Each is linked with ALOX15B in more than 2 cancer types. Because this analysis shows association rather than direction, both ALOX15B-to-partner and partner-to-ALOX15B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TCF19 grouped by ALOX15B-low versus ALOX15B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOX15B→partner) and Y-score (partner→ALOX15B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TCF19 →	+0.543	+2.673	.002	<.001	3	3
UCEC	MED9 →	+0.285	+1.839	<.001	<.001	3	3
COAD	MIR3115 →	+0.424	+3.357	<.001	.006	3	3
UCEC	SEC13 →	+0.338	+1.807	<.001	<.001	3	3
UCEC	GMPPB →	+0.333	+1.934	.005	.002	3	3
SKCM	ZNHIT3 →	+0.405	+2.669	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,512 associations by consensus.

TCF19 by ALOX15B expression — UCEC

Explore this box plot interactively →