ALOX15B

Across TCGA cell cohorts, ALOX15B RNA expression is significantly associated with the go_rna of many other GO terms, with 543 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ALOX15B-associated GO terms across cancer lineages are Energy derivation by oxidation of organic compounds, Male sex differentiation, and Carbon dioxide transmembrane transport. Each is linked with ALOX15B in more than 4 cancer types. Because this analysis shows association rather than direction, both ALOX15B-to-partner and partner-to-ALOX15B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy derivation by oxidation of organic compounds grouped by ALOX15B-low versus ALOX15B-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOX15B→partner) and Y-score (partner→ALOX15B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Energy derivation by oxidation of organic compounds →	+0.039	+0.202	.003	.003	3	5
KIDNEY	Male sex differentiation →	-0.090	-0.024	.001	.003	3	5
UPPER_AERODIGESTIVE_TRACT	Carbon dioxide transmembrane transport →	+1.223	+1.385	<.001	.002	3	4
BLOOD_Myeloma	Positive regulation of protein localization to nucleus →	+0.056	+0.121	.001	.003	3	4
BLOOD_Myeloma	Regulation of intrinsic apoptotic signaling pathway →	+0.045	+0.090	.004	.007	2	5
BLOOD_Myeloma	Intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator →	+0.090	+0.076	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 543 associations by consensus.

Energy derivation by oxidation of organic compounds by ALOX15B expression — SKIN

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