ALOX15B

Across TCGA cell cohorts, ALOX15B mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible ALOX15B-associated genes across cancer lineages are C9orf92, UGT3A1, and XAGE5. Each is linked with ALOX15B in more than 1 cancer types. Because this analysis shows association rather than direction, both ALOX15B-to-partner and partner-to-ALOX15B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C9orf92 grouped by ALOX15B-low versus ALOX15B-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOX15B→partner) and Y-score (partner→ALOX15B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C9orf92 →	+0.194	+5.369	<.001	.004	3	1
URINARY_TRACT	UGT3A1 →	+0.053	+4.217	<.001	.005	3	1
URINARY_TRACT	XAGE5 →	+0.265	+4.087	<.001	.009	3	1
URINARY_TRACT	A3GALT2 →	+0.063	+4.217	<.001	.005	3	1
URINARY_TRACT	CLEC9A →	+0.040	+5.044	<.001	<.001	3	1
URINARY_TRACT	LY6G6F →	+0.030	+4.087	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

C9orf92 by ALOX15B expression — SOFT_TISSUE

Explore this box plot interactively →