ALOX15

Across TCGA patient cohorts, ALOX15 protein abundance is significantly associated with the RNA expression of many other genes, with 5,240 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ALOX15-associated genes across cancer lineages are CLC, BCAS1, and CTSG. Each is linked with ALOX15 in more than 4 cancer types. Because this analysis shows association rather than direction, both ALOX15-to-partner and partner-to-ALOX15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALOX15 versus CLC in COAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOX15→partner) and Y-score (partner→ALOX15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CLC →	+1.790	+0.464	<.001	<.001	3	5
UCEC	BCAS1 →	+1.127	+1.233	<.001	<.001	3	4
HNSC	CTSG →	+1.153	+0.808	<.001	.002	3	3
HNSC	CEACAM4 →	+0.734	+0.746	.003	.002	3	3
HNSC	IL1RL1 →	+0.601	+0.560	.003	.005	3	3
COAD	PLS1 →	+0.799	+0.657	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,240 associations by consensus.

ALOX15 vs CLC — COAD

Explore this scatter interactively →