ALOX15

Across TCGA cell cohorts, ALOX15 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,872 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ALOX15-associated GO terms across cancer lineages are Lipoxin A4 biosynthetic process, Megakaryocyte differentiation, and Response to indole-3-methanol. Each is linked with ALOX15 in more than 7 cancer types. Because this analysis shows association rather than direction, both ALOX15-to-partner and partner-to-ALOX15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipoxin A4 biosynthetic process grouped by ALOX15-low versus ALOX15-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALOX15→partner) and Y-score (partner→ALOX15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Lipoxin A4 biosynthetic process →	+1.181	+2.413	<.001	<.001	3	7
URINARY_TRACT	Megakaryocyte differentiation →	-0.147	-0.953	.001	<.001	3	7
LUNG_NSCLC_LUAD	Response to indole-3-methanol →	+0.219	+0.519	<.001	.006	2	8
URINARY_TRACT	Regulation of cell chemotaxis to fibroblast growth factor →	-1.928	-1.218	<.001	.002	3	6
URINARY_TRACT	Regulation of endothelial cell chemotaxis to fibroblast growth factor →	-1.928	-1.218	<.001	.002	3	6
URINARY_TRACT	Positive regulation of establishment of T cell polarity →	-0.178	-1.344	.002	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,872 associations by consensus.

Lipoxin A4 biosynthetic process by ALOX15 expression — BREAST

Explore this box plot interactively →