ALMS1P1

Across TCGA pan-cancer cohorts, ALMS1P1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ALMS1P1 data layer compared with 2 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ALMS1P1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ALMS1P1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and KIRC show a favorable association.

BLCA, ACC, and DLBC are the cancer types where ALMS1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	All	0.417	0.273	.001	113	view →
ACC	DFS	Tertile	All	0.429	0.864	<.001	77	view →
DLBC	DFS	Quartile	II,III,IV	0.391	0.915	.005	54	view →
KIRC	DFS	Tertile	All	0.858	0.505	<.001	53	view →
READ	DFS	Median	III,IV	0.847	0.309	<.001	30	view →
LGG	OS	Median	All	0.936	0.852	<.001	30	view →
MESO	OS	Tertile	III,IV	0.787	0.178	.006	24	view →
UCEC	OS	Median	IV	0.216	0.599	.006	24	view →
THYM	DFS	Median	II,III,IV	0.664	0.967	.003	18	view →
UCS	OS	Median	II,III,IV	0.641	0.256	.010	18	view →
CESC	OS	Quartile	II,III,IV	0.934	0.722	.019	14	view →
LUAD	DFS	Median	II,III,IV	0.409	0.151	.003	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

ALMS1P1–BLCA (DFS)

Open the BLCA breakdown →