ALMS1

Across TCGA patient cohorts, ALMS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,919 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALMS1-associated proteins across cancer lineages are WRNIP1, CELF1, and PRPF4. Each is linked with ALMS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ALMS1-to-partner and partner-to-ALMS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALMS1 versus WRNIP1 in LSCC, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALMS1→partner) and Y-score (partner→ALMS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WRNIP1 →	+0.418	+0.559	<.001	<.001	3	7
LSCC	CELF1 →	+0.269	+0.570	<.001	<.001	3	6
GBM	PRPF4 →	+0.274	+0.379	<.001	<.001	3	5
GBM	RBBP5 →	+0.254	+0.341	<.001	<.001	3	5
GBM	RBM39 →	+0.238	+0.337	<.001	<.001	3	5
GBM	ZNF830 →	+0.395	+0.404	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,919 associations by consensus.

ALMS1 vs WRNIP1 — LSCC

Explore this scatter interactively →