ALLC

Across TCGA pan-cancer cohorts, ALLC Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ALLC data layer compared with 23 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ALLC Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ALLC expression acts as an unfavorable survival marker, although some lineages such as LUSC show a favorable association.

BLCA, READ, and LUAD are the cancer types where ALLC Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.094	0.694	<.001	30	view →
READ	OS	Median	II,III,IV	0.173	0.818	<.001	21	view →
LUAD	OS	Median	All	0.362	0.676	.011	6	view →
LUSC	DFS	Median	All	0.730	0.368	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ALLC–BLCA (OS)

Open the BLCA breakdown →