ALKBH8

Across TCGA patient cohorts, ALKBH8 protein abundance is significantly associated with the RNA expression of many other genes, with 5,966 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALKBH8-associated genes across cancer lineages are CWF19L2, PAWR, and RPL34P17. Each is linked with ALKBH8 in more than 2 cancer types. Because this analysis shows association rather than direction, both ALKBH8-to-partner and partner-to-ALKBH8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALKBH8 versus CWF19L2 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH8→partner) and Y-score (partner→ALKBH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CWF19L2 →	+0.442	+0.298	<.001	<.001	3	3
GBM	PAWR →	-0.662	-0.183	.005	.006	3	3
GBM	RPL34P17 →	-1.340	-0.277	<.001	<.001	3	2
BRCA	CADM3 →	+0.524	+0.173	.007	.005	3	2
LSCC	LINC02068 →	-0.584	-0.099	.001	.003	3	2
PDAC	RPS2P39 →	+0.262	+0.316	.007	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,966 associations by consensus.

ALKBH8 vs CWF19L2 — BRCA

Explore this scatter interactively →