Across TCGA pan-cancer cohorts, ALKBH2 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ALKBH2 data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ALKBH2 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ALKBH2 expression acts as an unfavorable survival marker.

BLCA are the cancer types where ALKBH2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	All	0.100	0.626	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: ALKBH2 tumor-vs-normal RNA expression · all ALKBH2 data types