Across TCGA patient cohorts, ALKBH2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,234 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALKBH2-associated proteins across cancer lineages are CDC73, MTREX, and POLR2E. Each is linked with ALKBH2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ALKBH2-to-partner and partner-to-ALKBH2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH2→partner) and Y-score (partner→ALKBH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CDC73 →	+0.362	+0.547	<.001	<.001	3	9
GBM	MTREX →	+0.323	+0.422	<.001	<.001	3	8
LSCC	POLR2E →	+0.215	+0.573	<.001	<.001	3	8
BRCA	PRCC →	+0.406	+0.778	<.001	<.001	3	8
GBM	ADNP →	+0.370	+0.463	<.001	<.001	3	8
LSCC	CMSS1 →	+0.550	+0.630	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,234 associations by consensus.

Exploration

ALKBH2 survival (RNA) · tumor vs normal (RNA) · all ALKBH2 data types