Across TCGA patient cohorts, ALKBH2 mutation is significantly associated with the RNA expression of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALKBH2-associated genes across cancer lineages are RN7SL554P, RPL22P14, and LINC01784. Each is linked with ALKBH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALKBH2-to-partner and partner-to-ALKBH2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH2→partner) and Y-score (partner→ALKBH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL554P →	+0.087	+4.199	<.001	.009	3	2
UCEC	RPL22P14 →	+0.134	+2.940	<.001	.005	3	2
PRAD	LINC01784 →	+0.104	+7.939	<.001	.008	3	1
PRAD	DLGAP5P2 →	+0.084	+7.939	<.001	.008	3	1
COAD	RNU6-694P →	+0.443	+5.893	<.001	.002	3	1
COAD	COMMD4P2 →	+0.199	+5.357	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

Exploration

ALKBH2 survival (RNA) · tumor vs normal (RNA) · all ALKBH2 data types