Across TCGA patient cohorts, ALKBH2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible ALKBH2-associated genes across cancer lineages are GMP, Chondrocytes, and MPP. Each is linked with ALKBH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALKBH2-to-partner and partner-to-ALKBH2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH2→partner) and Y-score (partner→ALKBH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GMP →	+0.047	+4.264	.025	.024	3	2
SKCM	Chondrocytes →	+0.036	+2.923	<.001	.047	3	1
LUSC	MPP →	+0.021	+4.694	<.001	.014	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

ALKBH2 survival (RNA) · tumor vs normal (RNA) · all ALKBH2 data types