Across TCGA cell cohorts, ALKBH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,568 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ALKBH2-associated GO terms across cancer lineages are Cell-substrate adhesion, Regulation of hydrolase activity, and Positive regulation of inflammatory response. Each is linked with ALKBH2 in more than 11 cancer types. Because this analysis shows association rather than direction, both ALKBH2-to-partner and partner-to-ALKBH2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH2→partner) and Y-score (partner→ALKBH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cell-substrate adhesion →	-0.194	-1.258	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Regulation of hydrolase activity →	-0.052	-0.862	<.001	<.001	3	11
CNS	Positive regulation of inflammatory response →	-0.114	-0.970	<.001	<.001	3	11
BONE	Endodermal cell differentiation →	-0.225	-1.344	<.001	<.001	3	11
BONE	Cell-matrix adhesion →	-0.203	-1.183	<.001	<.001	3	10
BREAST	Negative regulation of cell adhesion →	-0.098	-0.878	.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,568 associations by consensus.

Exploration

ALKBH2 survival (RNA) · tumor vs normal (RNA) · all ALKBH2 data types