ALKBH1

Across TCGA patient cohorts, ALKBH1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,602 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALKBH1-associated genes across cancer lineages are TTC8, GLRX5, and MFF-DT. Each is linked with ALKBH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ALKBH1-to-partner and partner-to-ALKBH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALKBH1 versus TTC8 in BRCA, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKBH1→partner) and Y-score (partner→ALKBH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TTC8 →	+0.728	+0.302	<.001	.001	3	3
LUAD	GLRX5 →	+0.385	+0.181	<.001	.004	3	2
LUAD	MFF-DT →	-0.528	-0.219	<.001	.009	3	2
PDAC	LINC00996 →	-0.720	-0.240	<.001	<.001	3	2
LUAD	RASGRF1 →	-0.837	-0.245	.001	.001	3	2
BRCA	CNIH1 →	+0.532	+0.372	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,602 associations by consensus.

ALKBH1 vs TTC8 — BRCA

Explore this scatter interactively →