Across TCGA patient cohorts, ALKAL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,771 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ALKAL2-associated proteins across cancer lineages are ERO1A, RAB31, and SMARCA2. Each is linked with ALKAL2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ALKAL2-to-partner and partner-to-ALKAL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKAL2→partner) and Y-score (partner→ALKAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ERO1A →	-0.536	-0.407	<.001	.001	3	5
OV	RAB31 →	-0.584	-1.078	<.001	<.001	3	5
HNSC	SMARCA2 →	+0.291	+0.498	<.001	.005	3	4
BRCA	ATP6V0D1 →	-0.290	-0.769	<.001	.006	3	4
OV	SRP54 →	-0.260	-1.173	.002	<.001	3	4
OV	COLGALT1 →	-0.393	-1.093	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,771 associations by consensus.

Exploration

ALKAL2 survival (RNA) · tumor vs normal (RNA) · all ALKAL2 data types