Across TCGA cell cohorts, ALKAL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,450 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ALKAL2-associated GO terms across cancer lineages are Negative regulation of binding, Regulation of cell cycle G1/S phase transition, and Regulation of G1/S transition of mitotic cell cycle. Each is linked with ALKAL2 in more than 7 cancer types. Because this analysis shows association rather than direction, both ALKAL2-to-partner and partner-to-ALKAL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKAL2→partner) and Y-score (partner→ALKAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of binding →	+0.066	+0.175	<.001	.003	3	8
OVARY	Regulation of cell cycle G1/S phase transition →	+0.057	+0.850	<.001	.006	2	8
BLOOD_Leukemia	Regulation of G1/S transition of mitotic cell cycle →	+0.051	+1.206	<.001	.003	3	7
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.099	+0.857	<.001	.007	3	6
OVARY	Regulation of myoblast fusion →	+0.113	+0.886	<.001	.006	3	6
LUNG_SCLC	Regulation of stem cell population maintenance →	+0.067	+0.856	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,450 associations by consensus.

Exploration

ALKAL2 survival (RNA) · tumor vs normal (RNA) · all ALKAL2 data types