Across TCGA patient cohorts, ALKAL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,796 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ALKAL1-associated proteins across cancer lineages are MFAP4, CAB39L, and FBLIM1. Each is linked with ALKAL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ALKAL1-to-partner and partner-to-ALKAL1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKAL1→partner) and Y-score (partner→ALKAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MFAP4 →	+1.474	+0.263	<.001	<.001	3	4
COAD	CAB39L →	+0.636	+0.772	<.001	<.001	3	4
CCRCC	FBLIM1 →	+0.653	+0.176	<.001	.003	3	4
CCRCC	FBLN5 →	+1.105	+0.246	<.001	<.001	3	4
CCRCC	THSD4 →	+0.678	+0.182	<.001	<.001	3	4
CCRCC	ACTN4 →	+0.304	+0.269	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,796 associations by consensus.

Exploration

ALKAL1 survival (RNA) · tumor vs normal (RNA) · all ALKAL1 data types