Across TCGA cell cohorts, ALKAL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 743 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible ALKAL1-associated GO terms across cancer lineages are Regulation of spindle assembly, Nuclear membrane reassembly, and Response to indole-3-methanol. Each is linked with ALKAL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ALKAL1-to-partner and partner-to-ALKAL1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALKAL1→partner) and Y-score (partner→ALKAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of spindle assembly →	+0.067	+0.375	.001	.002	2	5
URINARY_TRACT	Nuclear membrane reassembly →	+0.083	+0.454	<.001	.005	2	5
URINARY_TRACT	Response to indole-3-methanol →	+0.146	+0.442	.001	.007	3	4
URINARY_TRACT	Cellular response to indole-3-methanol →	+0.117	+0.347	.004	.007	3	4
PANCREAS	Positive regulation of matrix metallopeptidase secretion →	-0.210	-0.900	.002	.007	2	5
BLOOD_Leukemia	Positive regulation of pattern recognition receptor signaling pathway →	+0.025	+0.443	.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 743 associations by consensus.

Exploration

ALKAL1 survival (RNA) · tumor vs normal (RNA) · all ALKAL1 data types