ALG8

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ALG8 protein abundance is significantly associated with the RNA expression of many other genes, with 6,396 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALG8-associated genes across cancer lineages are PRDM8, B3GNT9, and CRYAB. Each is linked with ALG8 in more than 3 cancer types. Because this analysis shows association rather than direction, both ALG8-to-partner and partner-to-ALG8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALG8 versus PRDM8 in LUAD, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG8→partner) and Y-score (partner→ALG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADPRDM8 →-0.432-0.389.007<.00134
OVB3GNT9 →-0.708-0.290.002.00333
LSCCCRYAB →-0.965-0.385.005.00133
LSCCFBXO6 →+0.481+0.292<.001<.00133
GBMDGKI →-0.971-0.349.001.00233
COADITGA5 →-0.815-0.235.002.00433
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,396 associations by consensus.

ALG8 vs PRDM8 — LUAD

Per-sample scatter of ALG8 vs PRDM8 in LUAD (Pearson r = -0.27).

Explore this scatter interactively →

Exploration