ALG8

Across TCGA cell cohorts, ALG8 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,989 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ALG8-associated GO terms across cancer lineages are Asparaginyl-tRNA aminoacylation, Centriole elongation, and Nuclear pore organization. Each is linked with ALG8 in more than 13 cancer types. Because this analysis shows association rather than direction, both ALG8-to-partner and partner-to-ALG8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Asparaginyl-tRNA aminoacylation grouped by ALG8-low versus ALG8-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG8→partner) and Y-score (partner→ALG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Asparaginyl-tRNA aminoacylation →	+0.158	+1.025	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Centriole elongation →	+0.131	+1.639	<.001	<.001	3	12
BONE	Nuclear pore organization →	+0.182	+0.752	<.001	<.001	3	11
LIVER	Mitotic intra-S DNA damage checkpoint signaling →	+0.150	+0.946	.004	<.001	3	10
BLOOD_Lymphoma	Negative regulation of double-strand break repair →	+0.061	+0.634	<.001	<.001	3	10
OESOPHAGUS	Positive regulation of protein acetylation →	+0.135	+0.874	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,989 associations by consensus.

Asparaginyl-tRNA aminoacylation by ALG8 expression — OESOPHAGUS

Explore this box plot interactively →