ALG6

Across TCGA patient cohorts, ALG6 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,641 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALG6-associated proteins across cancer lineages are RFC2, MSH2, and FEN1. Each is linked with ALG6 in more than 6 cancer types. Because this analysis shows association rather than direction, both ALG6-to-partner and partner-to-ALG6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALG6 versus RFC2 in HNSC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG6→partner) and Y-score (partner→ALG6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RFC2 →	+0.481	+0.706	<.001	<.001	3	7
LSCC	MSH2 →	+0.456	+0.398	<.001	.003	3	7
OV	FEN1 →	+0.563	+0.503	.001	<.001	3	6
HNSC	POLD3 →	+0.411	+0.578	.001	.002	3	6
HNSC	PRPF8 →	+0.232	+0.795	<.001	<.001	3	6
LSCC	RCC2 →	+0.381	+0.418	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,641 associations by consensus.

ALG6 vs RFC2 — HNSC

Explore this scatter interactively →