ALG6

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ALG6 protein abundance is significantly associated with the RNA expression of many other genes, with 4,541 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALG6-associated genes across cancer lineages are STX4, MYH3, and ABTB1. Each is linked with ALG6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ALG6-to-partner and partner-to-ALG6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALG6 versus STX4 in UCEC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG6→partner) and Y-score (partner→ALG6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSTX4 →-0.660-0.661<.001<.00132
HNSCMYH3 →-1.328-0.312<.001<.00132
UCECABTB1 →-0.534-0.721.001<.00132
GBMCYTIP →-0.729-0.315.004.00732
UCECHVCN1 →-0.365-0.555.009.00132
COADPSTPIP1 →-0.590-0.333<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,541 associations by consensus.

ALG6 vs STX4 — UCEC

Per-sample scatter of ALG6 vs STX4 in UCEC (Pearson r = -0.38).

Explore this scatter interactively →

Exploration