Across TCGA patient cohorts, ALG5 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,166 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ALG5-associated GO terms across cancer lineages are Negative regulation of prostaglandin biosynthetic process, Retrograde transport, vesicle recycling within Golgi, and Box C/D snoRNP assembly. Each is linked with ALG5 in more than 22 cancer types. Because this analysis shows association rather than direction, both ALG5-to-partner and partner-to-ALG5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG5→partner) and Y-score (partner→ALG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Negative regulation of prostaglandin biosynthetic process →	+0.127	+1.483	<.001	<.001	3	23
ACC	Retrograde transport, vesicle recycling within Golgi →	+0.059	+0.990	<.001	.002	3	22
LAML	Box C/D snoRNP assembly →	+0.047	+0.362	<.001	<.001	3	22
UVM	CUT catabolic process →	+0.056	+1.225	<.001	<.001	3	21
ACC	Short-chain fatty acid catabolic process →	+0.076	+0.941	<.001	<.001	3	20
SKCM	Immunoglobulin V(D)J recombination →	+0.052	+0.647	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,166 associations by consensus.

Exploration

ALG5 survival (RNA) · tumor vs normal (RNA) · all ALG5 data types