ALG5

Across TCGA patient cohorts, ALG5 protein abundance is significantly associated with the RNA expression of many other genes, with 15,065 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALG5-associated genes across cancer lineages are WDR53, CBX1, and RBSN. Each is linked with ALG5 in more than 5 cancer types. Because this analysis shows association rather than direction, both ALG5-to-partner and partner-to-ALG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALG5 versus WDR53 in HNSC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG5→partner) and Y-score (partner→ALG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	WDR53 →	-0.742	-0.326	.001	<.001	3	6
HNSC	CBX1 →	-0.754	-0.303	.003	.001	3	6
COAD	RBSN →	-0.325	-0.233	<.001	.006	3	6
COAD	NCS1 →	-0.757	-0.323	<.001	<.001	3	5
LSCC	SMC3 →	-0.471	-0.415	<.001	<.001	3	5
UCEC	VAT1 →	-0.709	-0.403	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,065 associations by consensus.

ALG5 vs WDR53 — HNSC

Explore this scatter interactively →