ALG5

Across TCGA patient cohorts, ALG5 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,330 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALG5-associated proteins across cancer lineages are RPN1, DPAGT1, and ALG11. Each is linked with ALG5 in more than 9 cancer types. Because this analysis shows association rather than direction, both ALG5-to-partner and partner-to-ALG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALG5 versus RPN1 in UCEC, with a Pearson correlation of 0.82.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG5→partner) and Y-score (partner→ALG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPN1 →	+0.635	+0.572	<.001	<.001	3	10
UCEC	DPAGT1 →	+0.896	+0.572	<.001	<.001	3	10
UCEC	ALG11 →	+0.552	+0.536	<.001	<.001	3	10
BRCA	RPN2 →	+0.646	+0.619	<.001	<.001	3	9
BRCA	SRPRB →	+0.638	+0.507	<.001	<.001	3	9
BRCA	TRAM1 →	+0.781	+0.558	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,330 associations by consensus.

ALG5 vs RPN1 — UCEC

Explore this scatter interactively →