Q-omics provides the consensus-scored ALG3P1 profile across patient tissues and cancer cell-line models. ALG3P1 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, ALG3P1 is differentially expressed in 6, with the highest sampling consensus in COAD. Additionally, ALG3P1 RNA expression shows 9,305 significant gene co-expression associations, with the highest sampling consensus in LAML. Together, these results highlight UCS, COAD, and LAML as cancer lineages where ALG3P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ALG3P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ALG3P1 survival associations across molecular data types. ALG3P1 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ALG3P1 RNA expression–survival associations across cancer types. High ALG3P1 expression shows unfavorable associations in CESC and THCA, but favorable associations in UCS, LUAD, SKCM and STAD. The UCS Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify UCS as the clearest survival context for ALG3P1 RNA expression.
This table summarizes ALG3P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for ALG3P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ALG3P1 shows higher tumor expression in COAD, ESCA, LUSC, BRCA, LIHC and HNSC. The COAD box plot shows higher ALG3P1 RNA expression in tumor versus normal tissue (log2 FC = +0.049, t-test p = .010).
This table shows molecular features associated with ALG3P1 in patient tissues and cancer cell lines. In patient samples, ALG3P1 shows the broadest associations at the RNA and protein expression levels, with LAML recurring as the lineage with the largest associated feature set.
