Across TCGA patient cohorts, ALG3 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,577 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALG3-associated proteins across cancer lineages are REXO4, DDX18, and DDX27. Each is linked with ALG3 in more than 8 cancer types. Because this analysis shows association rather than direction, both ALG3-to-partner and partner-to-ALG3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG3→partner) and Y-score (partner→ALG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	REXO4 →	+0.490	+0.828	<.001	<.001	3	9
BRCA	DDX18 →	+0.364	+0.331	<.001	<.001	3	8
BRCA	DDX27 →	+0.426	+0.571	<.001	<.001	3	8
BRCA	WDR43 →	+0.358	+0.541	<.001	<.001	3	8
LSCC	WDR75 →	+0.295	+0.796	<.001	<.001	3	8
LSCC	HEATR1 →	+0.329	+0.912	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,577 associations by consensus.

Exploration

ALG3 survival (RNA) · tumor vs normal (RNA) · all ALG3 data types