Across TCGA patient cohorts, ALG3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,216 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALG3-associated genes across cancer lineages are GYPC, TPSAB1, and ZDHHC15. Each is linked with ALG3 in more than 4 cancer types. Because this analysis shows association rather than direction, both ALG3-to-partner and partner-to-ALG3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG3→partner) and Y-score (partner→ALG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GYPC →	-0.725	-0.737	<.001	<.001	3	5
HNSC	TPSAB1 →	-1.430	-0.515	<.001	.003	3	5
OV	ZDHHC15 →	-0.678	-0.550	<.001	<.001	3	4
LSCC	COX17 →	+0.604	+0.582	.001	.001	3	4
UCEC	MYOCD →	-1.243	-0.698	<.001	<.001	3	4
UCEC	PGM5 →	-1.168	-0.527	.002	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,216 associations by consensus.

Exploration

ALG3 survival (RNA) · tumor vs normal (RNA) · all ALG3 data types