Across TCGA patient cohorts, ALG3 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,738 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ALG3-associated proteins across cancer lineages are SEC62, TFRC, and ATP2A2. Each is linked with ALG3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ALG3-to-partner and partner-to-ALG3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG3→partner) and Y-score (partner→ALG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEC62 →	+0.660	+0.709	<.001	<.001	3	8
HNSC	TFRC →	+0.771	+0.645	<.001	<.001	3	7
BRCA	ATP2A2 →	+0.613	+0.758	<.001	<.001	3	7
HNSC	STIM1_S257 →	+0.931	+0.824	.003	.001	3	7
PDAC	TMEM209 →	+0.398	+0.972	.002	.003	3	7
LUAD	CIR1_S394 →	+1.142	+0.961	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,738 associations by consensus.

Exploration

ALG3 survival (RNA) · tumor vs normal (RNA) · all ALG3 data types