Across TCGA cell cohorts, ALG3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,565 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ALG3-associated GO terms across cancer lineages are Multi-pass transmembrane protein insertion into ER membrane, Protein N-linked glycosylation, and tRNA export from nucleus. Each is linked with ALG3 in more than 11 cancer types. Because this analysis shows association rather than direction, both ALG3-to-partner and partner-to-ALG3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG3→partner) and Y-score (partner→ALG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Multi-pass transmembrane protein insertion into ER membrane →	+0.144	+1.045	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Protein N-linked glycosylation →	+0.063	+0.650	.001	.002	3	10
LIVER	tRNA export from nucleus →	+0.119	+0.900	.002	.001	3	9
LIVER	Mitochondrial tRNA wobble uridine modification →	+0.132	+0.910	.005	.001	3	9
LIVER	Post-translational protein targeting to membrane, translocation →	+0.098	+0.776	<.001	<.001	3	9
KIDNEY	Metaphase/anaphase transition of cell cycle →	+0.116	+0.525	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,565 associations by consensus.

Exploration

ALG3 survival (RNA) · tumor vs normal (RNA) · all ALG3 data types