ALG1L9P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, ALG1L9P RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of ALG1L9P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ALG1L9P RNA is repressed in tumor relative to normal tissue. In most cancer types ALG1L9P is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, LIHC, and LUAD are the cancer types where ALG1L9P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ALG1L9P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHAllIII,IV−0.604<.0019view →
LIHCMaleAll+0.561<.0019view →
LUADMaleAll+0.820<.0018view →
HNSCAllII,III,IV+0.354.0068view →
LUSCFemaleAll+0.752<.0017view →
BRCAAllIII,IV+0.599<.0016view →
CHOLMaleAll+1.360<.0015view →
READAllAll+0.513.0365view →
KIRPAllII,III,IV+0.454.0035view →
COADAllII,III,IV+0.290.0065view →
STADAllII,III,IV+0.577<.0014view →
BLCAAllAll+0.475.0104view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

ALG1L9P–KICH

Tumor-vs-normal expression box plot for ALG1L9P RNA in KICH.

Open the KICH breakdown →

Exploration