ALG1L15P

Across TCGA pan-cancer cohorts, ALG1L15P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ALG1L15P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher ALG1L15P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ALG1L15P expression acts as an unfavorable survival marker, although some lineages such as UCEC and CESC show a favorable association.

UVM, LGG, and ACC are the cancer types where ALG1L15P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Quartile	II,III,IV	0.421	0.728	.004	55	view →
LGG	DFS	Tertile	All	0.618	0.806	<.001	36	view →
ACC	DFS	Tertile	All	0.503	0.780	.002	35	view →
CHOL	OS	Median	All	0.179	0.888	.003	26	view →
UCEC	DFS	Median	IV	0.658	0.279	.009	26	view →
CESC	OS	Tertile	All	0.930	0.818	.001	20	view →
LUAD	OS	Quartile	III,IV	0.391	0.731	.010	18	view →
READ	DFS	Tertile	III,IV	1.000	0.359	.015	15	view →
THYM	DFS	Tertile	III,IV	1.000	0.235	.007	12	view →
LAML	DFS	Median	All	0.574	0.359	.028	10	view →
THCA	DFS	Median	IV	0.645	0.881	.037	9	view →
LUSC	OS	Median	All	0.463	0.329	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ALG1L15P–UVM (DFS)

Open the UVM breakdown →