ALG13

Across TCGA patient cohorts, ALG13 mutation is significantly associated with the RNA expression of many other genes, with 4,372 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALG13-associated genes across cancer lineages are GET3, IER3IP1, and MYO15B. Each is linked with ALG13 in more than 3 cancer types. Because this analysis shows association rather than direction, both ALG13-to-partner and partner-to-ALG13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GET3 grouped by ALG13-low versus ALG13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG13→partner) and Y-score (partner→ALG13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GET3 →	+0.329	+1.337	<.001	<.001	3	4
UCEC	IER3IP1 →	+0.268	+1.463	.007	.001	3	4
COAD	MYO15B →	-0.828	-3.321	<.001	.009	3	3
COAD	CENPU →	+0.785	+3.000	<.001	.001	3	3
UCEC	UBASH3B →	+0.474	+1.979	<.001	<.001	3	3
COAD	SKA1 →	+0.839	+3.013	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,372 associations by consensus.

GET3 by ALG13 expression — UCEC

Explore this box plot interactively →