ALG13

Across TCGA cell cohorts, ALG13 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,465 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ALG13-associated GO terms across cancer lineages are Translation reinitiation, Replication fork processing, and Microtubule polymerization. Each is linked with ALG13 in more than 9 cancer types. Because this analysis shows association rather than direction, both ALG13-to-partner and partner-to-ALG13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Translation reinitiation grouped by ALG13-low versus ALG13-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG13→partner) and Y-score (partner→ALG13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Translation reinitiation →	+0.082	+0.825	.008	.002	3	10
BLOOD_Lymphoma	Replication fork processing →	+0.072	+0.495	.001	.007	2	10
LIVER	Microtubule polymerization →	+0.097	+0.870	.005	.004	3	9
LARGE_INTESTINE	Mitotic recombination →	+0.081	+0.660	<.001	<.001	3	9
LARGE_INTESTINE	Homologous recombination →	+0.057	+0.470	<.001	.004	3	8
LARGE_INTESTINE	Positive regulation of maintenance of sister chromatid cohesion →	+0.058	+0.496	.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,465 associations by consensus.

Translation reinitiation by ALG13 expression — LUNG_NSCLC_LUSC

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