ALG13

Across TCGA cell cohorts, ALG13 mutation is significantly associated with the RNA expression of many other genes, with 351 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ALG13-associated genes across cancer lineages are ADAM7, KRTAP19-3, and TBL1Y. Each is linked with ALG13 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALG13-to-partner and partner-to-ALG13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM7 grouped by ALG13-low versus ALG13-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG13→partner) and Y-score (partner→ALG13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ADAM7 →	+0.003	+2.538	<.001	.005	3	2
CNS	KRTAP19-3 →	+0.071	+5.321	<.001	.005	3	2
LUNG_NSCLC_LUSC	TBL1Y →	+0.053	+4.643	<.001	.008	3	1
SKIN	DPPA3 →	+0.027	+4.273	.002	.006	3	1
SKIN	NXPE1 →	+0.038	+4.095	<.001	.009	3	1
LARGE_INTESTINE	HSCB →	+0.639	+3.364	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 351 associations by consensus.

ADAM7 by ALG13 expression — LARGE_INTESTINE

Explore this box plot interactively →