Across TCGA patient cohorts, ALG12 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,483 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALG12-associated proteins across cancer lineages are ST13, MSI2, and CCDC134. Each is linked with ALG12 in more than 4 cancer types. Because this analysis shows association rather than direction, both ALG12-to-partner and partner-to-ALG12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG12→partner) and Y-score (partner→ALG12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ST13 →	+0.325	+0.286	<.001	<.001	3	5
LSCC	MSI2 →	+0.548	+0.391	<.001	<.001	3	5
COAD	CCDC134 →	+0.289	+0.302	<.001	<.001	3	4
GBM	SRSF9 →	+0.374	+0.322	.001	.005	3	4
GBM	HNRNPLL →	+0.196	+0.266	.003	.007	3	4
GBM	XRCC6 →	+0.274	+0.360	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,483 associations by consensus.

Exploration

ALG12 survival (RNA) · tumor vs normal (RNA) · all ALG12 data types