Across TCGA patient cohorts, ALG12 protein abundance is significantly associated with the RNA expression of many other genes, with 8,591 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALG12-associated genes across cancer lineages are INF2, RAB5B, and TXN2. Each is linked with ALG12 in more than 4 cancer types. Because this analysis shows association rather than direction, both ALG12-to-partner and partner-to-ALG12 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG12→partner) and Y-score (partner→ALG12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INF2 →	-0.706	-0.393	<.001	<.001	3	5
COAD	RAB5B →	-0.307	-0.258	.006	.004	3	3
BRCA	TXN2 →	+0.499	+0.377	.002	.005	3	3
UCEC	ZNF14 →	-0.458	-0.373	.009	.002	3	3
LSCC	PRR5 →	+0.507	+0.280	<.001	<.001	3	3
OV	ARFGAP3 →	+0.547	+0.359	.005	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,591 associations by consensus.

Exploration

ALG12 survival (RNA) · tumor vs normal (RNA) · all ALG12 data types