Across TCGA patient cohorts, ALG12 mutation is significantly associated with the RNA expression of many other genes, with 675 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALG12-associated genes across cancer lineages are CTBP2P10, VN1R91P, and IGHD1-26. Each is linked with ALG12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ALG12-to-partner and partner-to-ALG12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG12→partner) and Y-score (partner→ALG12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	CTBP2P10 →	+0.033	+3.979	.008	.006	3	2
UCEC	VN1R91P →	+0.233	+3.243	<.001	<.001	3	2
UCEC	IGHD1-26 →	+0.532	+2.677	<.001	.005	3	2
COAD	LINC01241 →	+0.122	+5.790	.004	.003	3	1
COAD	VENTXP7 →	+0.224	+5.283	<.001	.006	3	1
COAD	RNU6-1057P →	+0.396	+5.516	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 675 associations by consensus.

Exploration

ALG12 survival (RNA) · tumor vs normal (RNA) · all ALG12 data types