Across TCGA cell cohorts, ALG12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,026 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ALG12-associated GO terms across cancer lineages are Positive regulation of T-helper 17 cell lineage commitment, Golgi transport vesicle coating, and COPI coating of Golgi vesicle. Each is linked with ALG12 in more than 14 cancer types. Because this analysis shows association rather than direction, both ALG12-to-partner and partner-to-ALG12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG12→partner) and Y-score (partner→ALG12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of T-helper 17 cell lineage commitment →	+0.204	+0.732	<.001	.006	3	15
UPPER_AERODIGESTIVE_TRACT	Golgi transport vesicle coating →	+0.131	+1.100	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	COPI coating of Golgi vesicle →	+0.131	+1.100	<.001	<.001	3	13
STOMACH	Symbiont-mediated disruption of host cellular anatomical structure →	+0.126	+0.974	.003	.002	3	13
STOMACH	Symbiont-mediated disruption of host anatomical structure →	+0.126	+0.974	.003	.002	3	13
SKIN	Positive regulation of protein localization to endoplasmic reticulum →	+0.128	+0.918	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,026 associations by consensus.

Exploration

ALG12 survival (RNA) · tumor vs normal (RNA) · all ALG12 data types