ALG11

Across TCGA patient cohorts, ALG11 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,807 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALG11-associated proteins across cancer lineages are ARHGEF7, SUCLA2, and SUGT1. Each is linked with ALG11 in more than 7 cancer types. Because this analysis shows association rather than direction, both ALG11-to-partner and partner-to-ALG11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALG11 versus ARHGEF7 in CCRCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG11→partner) and Y-score (partner→ALG11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ARHGEF7 →	+0.248	+0.327	<.001	<.001	3	8
GBM	SUCLA2 →	+0.391	+0.309	.001	.002	3	7
COAD	SUGT1 →	+0.436	+0.323	<.001	<.001	3	6
BRCA	COG2 →	+0.243	+0.343	<.001	<.001	3	6
GBM	COG3 →	+0.245	+0.328	.001	<.001	3	6
GBM	TDRD3 →	+0.304	+0.404	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,807 associations by consensus.

ALG11 vs ARHGEF7 — CCRCC

Explore this scatter interactively →