ALG10

Across TCGA pan-cancer cohorts, ALG10 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ALG10 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ALG10 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ALG10 expression acts as an unfavorable survival marker.

COAD, SARC, and SKCM are the cancer types where ALG10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.184	0.803	<.001	12	view →
SARC	OS	Median	All	0.162	0.767	.002	6	view →
SKCM	OS	Median	All	0.135	0.327	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ALG10–COAD (OS)

Open the COAD breakdown →