ALG10

Across TCGA patient cohorts, ALG10 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,636 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ALG10-associated proteins across cancer lineages are VEZF1, WDR5, and WRNIP1. Each is linked with ALG10 in more than 4 cancer types. Because this analysis shows association rather than direction, both ALG10-to-partner and partner-to-ALG10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALG10 versus VEZF1 in HNSC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG10→partner) and Y-score (partner→ALG10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VEZF1 →	+0.422	+0.917	<.001	<.001	3	5
LSCC	WDR5 →	+0.285	+0.739	<.001	<.001	3	5
LSCC	WRNIP1 →	+0.277	+0.485	<.001	<.001	3	5
LSCC	XPO1 →	+0.284	+0.745	<.001	<.001	3	5
LSCC	MSH6 →	+0.700	+0.759	<.001	<.001	3	5
LSCC	ORC3 →	+0.405	+0.725	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,636 associations by consensus.

ALG10 vs VEZF1 — HNSC

Explore this scatter interactively →