ALG10

Across TCGA patient cohorts, ALG10 mutation is significantly associated with the RNA expression of many other genes, with 2,111 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ALG10-associated genes across cancer lineages are RNA5SP412, RN7SL134P, and SUGT1P4. Each is linked with ALG10 in more than 2 cancer types. Because this analysis shows association rather than direction, both ALG10-to-partner and partner-to-ALG10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by ALG10-low versus ALG10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALG10→partner) and Y-score (partner→ALG10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.470	+1.774	<.001	.009	3	3
UCEC	RN7SL134P →	+0.136	+2.406	<.001	<.001	3	3
LUSC	SUGT1P4 →	+0.220	+5.578	<.001	.002	3	3
CESC	RPS23P5 →	+0.087	+4.539	<.001	.008	3	2
CESC	LINC02500 →	+0.910	+5.144	<.001	.003	3	2
CESC	VTRNA2-2P →	+0.361	+4.601	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,111 associations by consensus.

RNA5SP412 by ALG10 expression — UCEC

Explore this box plot interactively →