ALDOC

Across TCGA pan-cancer cohorts, ALDOC Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ALDOC data layer compared with 25 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher ALDOC Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ALDOC expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

KIRP, SCLC, and PRAD are the cancer types where ALDOC Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.141	0.904	<.001	36	view →
SCLC	OS	Median	II,III,IV	0.082	0.648	<.001	24	view →
PRAD	DFS	Median	All	0.617	0.886	.035	6	view →
SKCM	OS	Median	II,III,IV	0.278	0.739	.045	6	view →
UCEC	DFS	Median	II,III,IV	1.000	0.444	.039	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ALDOC–KIRP (OS)

Open the KIRP breakdown →