ALDOB

Across TCGA cell cohorts, ALDOB RNA expression is significantly associated with the go_rna of many other GO terms, with 1,736 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ALDOB-associated GO terms across cancer lineages are Regulation of vacuole organization, Regulation of TORC1 signaling, and Positive regulation of TOR signaling. Each is linked with ALDOB in more than 6 cancer types. Because this analysis shows association rather than direction, both ALDOB-to-partner and partner-to-ALDOB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of vacuole organization grouped by ALDOB-low versus ALDOB-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDOB→partner) and Y-score (partner→ALDOB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of vacuole organization →	+0.055	+0.097	<.001	.005	3	7
LUNG_SCLC	Regulation of TORC1 signaling →	+0.064	+0.131	<.001	.002	2	7
LUNG_SCLC	Positive regulation of TOR signaling →	+0.053	+0.151	.002	.001	3	6
BLOOD_Leukemia	Regulation of RNA stability →	+0.031	+0.083	.003	.001	3	6
BLOOD_Leukemia	Regulation of mRNA stability →	+0.027	+0.080	.003	.001	3	6
LUNG_SCLC	Regulation of TOR signaling →	+0.054	+0.202	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,736 associations by consensus.

Regulation of vacuole organization by ALDOB expression — OVARY

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