ALDOB

Across TCGA cell cohorts, ALDOB mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ALDOB-associated genes across cancer lineages are WFDC8, ADIPOQ, and PABPC1L2A. Each is linked with ALDOB in more than 1 cancer types. Because this analysis shows association rather than direction, both ALDOB-to-partner and partner-to-ALDOB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WFDC8 grouped by ALDOB-low versus ALDOB-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDOB→partner) and Y-score (partner→ALDOB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	WFDC8 →	+0.022	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	ADIPOQ →	+0.013	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	PABPC1L2A →	+0.033	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	FAM24A →	+0.073	+6.247	<.001	<.001	3	1
CNS	CST5 →	+0.113	+4.981	<.001	.008	3	1
SKIN	GYS2 →	+0.016	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

WFDC8 by ALDOB expression — BLOOD_Lymphoma

Explore this box plot interactively →