ALDOA

Across TCGA patient cohorts, ALDOA protein abundance is significantly associated with the RNA expression of many other genes, with 5,968 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ALDOA-associated genes across cancer lineages are CCNO, LRFN1, and TMEM208. Each is linked with ALDOA in more than 2 cancer types. Because this analysis shows association rather than direction, both ALDOA-to-partner and partner-to-ALDOA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ALDOA versus CCNO in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ALDOA→partner) and Y-score (partner→ALDOA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CCNO →	+1.772	+0.859	.002	.003	3	3
GBM	LRFN1 →	-0.757	-0.582	.003	.004	3	3
LSCC	TMEM208 →	+0.333	+0.577	.007	.004	3	3
CCRCC	HNRNPA3 →	-0.565	-1.070	<.001	.003	3	3
LSCC	GALE →	+0.753	+0.636	.005	.005	3	3
HNSC	STS →	+0.940	+1.083	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,968 associations by consensus.

ALDOA vs CCNO — BRCA

Explore this scatter interactively →