ALDH7A1P4

Across TCGA pan-cancer cohorts, ALDH7A1P4 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated ALDH7A1P4 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ALDH7A1P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ALDH7A1P4 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

KIRC, OV, and COAD are the cancer types where ALDH7A1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.405	0.643	.012	66	view →
OV	DFS	Tertile	All	0.481	0.153	.022	42	view →
COAD	DFS	Tertile	III,IV	0.167	0.667	.029	18	view →
THYM	DFS	Tertile	All	0.092	0.871	<.001	18	view →
SARC	DFS	Tertile	All	0.186	0.612	.023	18	view →
STAD	DFS	Tertile	All	0.474	0.724	.028	9	view →
ESCA	OS	Tertile	II,III,IV	0.269	0.692	.003	9	view →
PCPG	OS	Tertile	All	0.078	0.954	.013	9	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

ALDH7A1P4–KIRC (OS)

Open the KIRC breakdown →