ALDH7A1P3

Across TCGA pan-cancer cohorts, ALDH7A1P3 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated ALDH7A1P3 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher ALDH7A1P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ALDH7A1P3 expression acts as an unfavorable survival marker, although some lineages such as PAAD and KIRP show a favorable association.

MESO, COAD, and THYM are the cancer types where ALDH7A1P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.087	0.591	<.001	126	view →
COAD	OS	Tertile	III,IV	0.425	0.793	.001	99	view →
THYM	OS	Tertile	III,IV	0.212	0.953	.009	45	view →
KIRC	DFS	Tertile	II,III,IV	0.245	0.685	<.001	36	view →
PAAD	OS	Tertile	All	1.000	0.375	.027	18	view →
KIRP	DFS	Tertile	III,IV	1.000	0.306	.034	15	view →
SKCM	DFS	Tertile	All	0.543	0.737	.013	12	view →
UCEC	OS	Tertile	III,IV	0.394	0.626	.043	12	view →
BLCA	OS	Tertile	All	1.000	0.335	.027	9	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
LUAD	OS	Tertile	All	0.657	0.816	.042	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

ALDH7A1P3–MESO (OS)

Open the MESO breakdown →